Hotels in Greenville

Free cancellation options if plans change
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Check prices for these dates

Tonight
Feb 14 - Feb 15
Tomorrow
Feb 15 - Feb 16
This weekend
Feb 14 - Feb 16
Next weekend
Feb 21 - Feb 23

Where to stay in Greenville?

On a rooftop patio

Use code VALENPOWER for an extra 10% off your next getaway

One Key™ members get an extra 10% off hotels, book by Feb 17, travel between Feb 6 through Aug 31 (US customers only).*T&Cs apply

Learn more about Greenville

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Frequently asked questions

Can I book refundable hotels in Greenville?
If you need the flexibility to change your travel plans to Greenville, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Greenville be like during my trip?
With an average temperature of 77°F during the coldest months, Greenville is a great place to visit any time of year.
Why should I book my Greenville accommodation with Hotels.com?
There are plenty of reasons to book your Greenville travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.