Hotels in Santa Isabel

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Check prices for these dates

Tonight
May 8 - May 9
Tomorrow
May 9 - May 10
This weekend
May 9 - May 11
Next weekend
May 16 - May 18

Where to stay in Santa Isabel?

Cabins on paradise San Blas island
Beach

Cabins on paradise San Blas island

2.0 star property
The price is $329
includes taxes & fees
$299 per night
May 9 - May 10
Cabins on paradise San Blas island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Isabel

While in the area, you can enjoy nearby attractions like Porvenir Museum.

See all hotels in Santa Isabel
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers recommend in Santa Isabel?
Guests like Coral Lodge.
Can I book a refundable accommodation in Santa Isabel?
If you need the flexibility to change your plans to Santa Isabel, most hotels provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa Isabel be like during my vacation?
With an average temperature of 78°F during the coldest months, Santa Isabel is a great place to visit any time of year.
Why should I book my Santa Isabel accommodation with Hotels.com?
There are lots of reasons to book your Santa Isabel trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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