Hotels in Mesopotamia

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Check prices for these dates

Tonight
Jul 15 - Jul 16
Tomorrow
Jul 16 - Jul 17
This weekend
Jul 18 - Jul 20
Next weekend
Jul 25 - Jul 27

Where to stay in Mesopotamia?

To Spiti tis Sofias
Interior

To Spiti tis Sofias

$63 nightly
The price is $74
Jul 29 - Jul 30
Total includes taxes and fees
To Spiti tis Sofias
Anesis Hotel
Property grounds

Anesis Hotel

2.0 star property
9.0 out of 10, Wonderful, (9)
$57 nightly
The price is $66
Jul 17 - Jul 18
Total includes taxes and fees
Anesis Hotel
Esperos Palace Luxury & Spa Hotel
Breakfast, lunch and dinner served

Esperos Palace Luxury & Spa Hotel

4.0 star property
9.0 out of 10, Wonderful, (83)
$98 nightly
The price is $124
Jul 17 - Jul 18
Total includes taxes and fees
Esperos Palace Luxury & Spa Hotel
Hotel Anastassiou
Front of property - evening/night

Hotel Anastassiou

2.0 star property
8.0 out of 10, Very Good, (62)
$44 nightly
The price is $53
Jul 24 - Jul 25
Total includes taxes and fees
Hotel Anastassiou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesopotamia

Kastoria Lake

Kastoria Lake is 1.3 mi (2.1 km) from central Kastoria, why not stop by during your stay.

See properties in Kastoria Lake
Kastoria Lake

Dragon's Lair

Dragon's Lair is 2.5 mi (4.1 km) from central Kastoria, why not stop by during your stay.

See properties in Dragon's Lair
Dragon's Lair

Holy Monastery of Panagias Mauriotissas

If you're interested in local churches, head to Holy Monastery of Panagias Mauriotissas located 2.5 mi (4.1 km) from central Kastoria.

See properties in Holy Monastery of Panagias Mauriotissas
Holy Monastery of Panagias Mauriotissas

Learn more about Mesopotamia

The region around Mesopotamia is home to attractions such as Kastoria Lake and Dragon's Lair.

See all hotels in Mesopotamia

Check out the Mesopotamia hotels guests love right now

Chloe Hotel

Chloe Hotel

10/10 Excellent
"Romantic and special. Highly recommend. Kastoria is a rare find. This hotel is a great getaway. "
Jeana 2-night trip
Posted 3 weeks ago
Chloe Hotel
Limneon Resort & Spa

Limneon Resort & Spa

10/10 Excellent
"The hotel is beautiful. Service and cleaniness foe this property is the BEST!!!!Friendly staff. "
rania 2-night trip
Posted 3 months ago
Limneon Resort & Spa
Hotel Anastassiou

Hotel Anastassiou

8/10 Good
"Nice simple stay."
Jeffrey 1-night trip
Posted 5 months ago
Hotel Anastassiou

Frequently asked questions

How much does a hotel room cost in Mesopotamia?
You can choose a great hotel in Mesopotamia from $53 with properties to suit all budgets and needs. If you're after an affordable hotel in Mesopotamia that meets all of your requirements, set your filters and then sort the results by "Price: low to high". If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Mesopotamia hotels?
Members can save up to 20% on select hotels in Mesopotamia. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.

Can I book Mesopotamia hotels with free cancellation?
To book a refundable Mesopotamia hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are the top Mesopotamia hotels with a pool?
For a little extra luxury, discover some of the best Mesopotamia hotels with a pool. You can select "Pool" in the "Amenities" filter of your search on Hotels.com to find even more places to stay in Mesopotamia with a pool.
What are some popular hotels in central Mesopotamia?
If you're looking for hotels in central Mesopotamia, check out Chloe Hotel and Kyknos De Luxe Hotel. Travelers love Chloe Hotel for its location, as well as the winery, restaurant and outdoor tennis court this hotel offers. Kyknos De Luxe Hotel is another popular central hotel with a terrace, free parking and a hair salon.
Are all taxes and fees included in the Mesopotamia hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
What hotels do travelers like in Mesopotamia?
Guests like To Spiti tis Sofias, Limneon Resort & Spa and Chloe Hotel.
Can I book a refundable hotel in Mesopotamia?
If you want the flexibility to change your travel plans to Mesopotamia, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay if I'm visiting Mesopotamia with my children?
Your kids are welcome at To Spiti tis Sofias.
What will the weather in Mesopotamia be like during my trip?
The warmest months in Mesopotamia are usually August and July with an average temp of 69°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are November and December.
Why should I book my Mesopotamia hotel with Hotels.com?
There are plenty of reasons to book your Mesopotamia travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Mesopotamia

Find out more about Mesopotamia

If you're looking to discover somewhere new, look no further than Mesopotamia. Whether you're planning to stay for a night or for the week, the area around Mesopotamia has accommodations to fit every need. Search for hotels in Mesopotamia with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Mesopotamia hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Mesopotamia hotel deals are here with our lowest price guarantee.