If you're looking for a place to get away, look no further than Charleston. Whether you're planning to stay for a night or for the week, the area around Charleston has accommodations to fit every need. Search for hotels in Charleston with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Charleston hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Charleston hotel deals are here with our lowest price guarantee.
Hotels in Charleston
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Where to stay in Charleston?

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.6 out of 10, (572)
$66 nightly
The price is $73
Jul 16 - Jul 17
Total includes taxes and fees

Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
6.8 out of 10, (389)
$70 nightly
The price is $78
Jul 27 - Jul 28
Total includes taxes and fees

Eagle Inn Charleston
Eagle Inn Charleston
6.8 out of 10, (100)
$66 nightly
The price is $73
Jul 16 - Jul 17
Total includes taxes and fees

Country Yard Inn and Suite
Country Yard Inn and Suite
7.2 out of 10, Good, (97)
$68 nightly
The price is $77
Jul 16 - Jul 17
Total includes taxes and fees

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1012)
$88 nightly
The price is $100
Aug 10 - Aug 11
Total includes taxes and fees

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1001)
$72 nightly
The price is $82
Jul 20 - Jul 21
Total includes taxes and fees

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1006)
$102 nightly
The price is $117
Jul 20 - Jul 21
Total includes taxes and fees

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very Good, (661)
$68 nightly
The price is $78
Jul 16 - Jul 17
Total includes taxes and fees

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1001)
$80 nightly
The price is $92
Jul 23 - Jul 24
Total includes taxes and fees

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
8.4 out of 10, Very Good, (268)
$89 nightly
The price is $102
Aug 10 - Aug 11
Total includes taxes and fees

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
6.6 out of 10, (543)
$67 nightly
The price is $76
Jul 22 - Jul 23
Total includes taxes and fees

Quality Inn Cairo I-57
Quality Inn Cairo I-57
6.6 out of 10, (261)
$74 nightly
The price is $82
Aug 2 - Aug 3
Total includes taxes and fees

Hampton Inn Sikeston
Hampton Inn Sikeston
8.8 out of 10, Excellent, (361)
$118 nightly
The price is $134
Jul 27 - Jul 28
Total includes taxes and fees

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
8.6 out of 10, Excellent, (412)
$108 nightly
The price is $122
Jul 20 - Jul 21
Total includes taxes and fees

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
10.0 out of 10, Exceptional, (14)
$122 nightly
The price is $138
Jul 21 - Jul 22
Total includes taxes and fees

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
7.4 out of 10, Good, (3)
$134 nightly
The price is $152
Jul 27 - Jul 28
Total includes taxes and fees

La Center Motel
La Center Motel
7.8 out of 10, Good, (14)
$59 nightly
The price is $63
Jul 16 - Jul 17
Total includes taxes and fees

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
8.0 out of 10, Very Good, (826)
$82 nightly
The price is $98
Jul 22 - Jul 23
Total includes taxes and fees

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
9.6 out of 10, Exceptional, (427)
$116 nightly
The price is $131
Jul 27 - Jul 28
Total includes taxes and fees

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
9.4 out of 10, Exceptional, (114)
$93 nightly
The price is $105
Jul 20 - Jul 21
Total includes taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Charleston
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Learn more about Charleston
Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.
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