Hotels in South San Francisco

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Check prices for these dates

Tonight
Apr 25 - Apr 26
Tomorrow
Apr 26 - Apr 27
This weekend
Apr 25 - Apr 27
Next weekend
May 2 - May 4

Where to stay in South San Francisco?

Comfort Inn and Suites San Francisco Airport North
In-room safe, desk, iron/ironing board, free cribs/infant beds

Comfort Inn and Suites San Francisco Airport North

2.5 star property
7.8 out of 10, Good, (1001)
The price is $114
includes taxes & fees
$97 per night
May 2 - May 3
Comfort Inn and Suites San Francisco Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
trending_down

Our prices for hotels in South San Francisco are cheapest in March

See average prices and weather for all months

Price trends for hotels in South San Francisco

Pricing is based on two traveler single night rates
Apr
$144
Average price during April is $144
May
$129
Average price during May is $129
Jun
$146
Average price during June is $146
Jul
$171
Average price during July is $171
Aug
$170
Average price during August is $170
Sep
$176
Average price during September is $176
Oct
$192
Average price during October is $192
Nov
$175
Average price during November is $175
Dec
$138
Average price during December is $138
Jan
$134
Average price during January is $134
Feb
$127
Average price during February is $127
Mar
$126
Average price during March is $126
Currently viewing crowd sizes and weather for April.

April

trending_flatModerate crowds
High 60°F / low 50°F. Sunny most days.
60°
weather_sun
April, Moderate crowds, average high temperature 60 degrees Fahrenheit, average low temperature 50 degrees Fahrenheit. Sunny most days.
50°
62°
weather_sun
May, High crowds, average high temperature 62 degrees Fahrenheit, average low temperature 52 degrees Fahrenheit. Sunny most days.
52°
65°
weather_sun
June, Moderate crowds, average high temperature 65 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
55°
66°
weather_sun
July, High crowds, average high temperature 66 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
56°
68°
weather_sun
August, High crowds, average high temperature 68 degrees Fahrenheit, average low temperature 58 degrees Fahrenheit. Sunny most days.
58°
69°
weather_sun
September, High crowds, average high temperature 69 degrees Fahrenheit, average low temperature 58 degrees Fahrenheit. Sunny most days.
58°
67°
weather_sun
October, Moderate crowds, average high temperature 67 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
56°
62°
weather_sun
November, Low crowds, average high temperature 62 degrees Fahrenheit, average low temperature 51 degrees Fahrenheit. Sunny most days.
51°
57°
weather_sun
December, Low crowds, average high temperature 57 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
48°
58°
weather_sun
January, Low crowds, average high temperature 58 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
48°
58°
weather_sun
February, Low crowds, average high temperature 58 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
48°
58°
weather_sun
March, Moderate crowds, average high temperature 58 degrees Fahrenheit, average low temperature 49 degrees Fahrenheit. Sunny most days.
49°
Monthly weather averages (˚F)
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Top neighborhoods in South San Francisco

#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.

The East Side

South San Francisco's The East Side neighborhood is home to attractions such as San Francisco Bay and San Bruno Point Park.

See properties in The East Side
The East Side

Top landmarks in South San Francisco

South San Francisco Convention Center

South San Francisco Convention Center is worth a visit, located 0.5 mi (0.8 km) from central South San Francisco. Hotels.com travelers also say the area is full of friendly people and has lots of nice beaches. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.

See properties in South San Francisco Convention Center
South San Francisco Convention Center

Learn more about South San Francisco

South San Francisco is well-known for its castle while top attractions include San Francisco Bay. Visitors to this family-friendly city speak highly of the restaurants whereas sights include South San Francisco Convention Center and Santa Cruz Mountains.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in South San Francisco?
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront, Home2 Suites by Hilton San Francisco Airport North and Airport Inn are all properties that our guests really like.
Where can I get free parking at my hotel in South San Francisco?
Park your car for free at Americana Inn.
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in South San Francisco?
Your animal companion is welcome at these pet-friendly hotels: DoubleTree by Hilton San Francisco South Airport Blvd, La Quinta Inn & Suites by Wyndham San Francisco Airport N, and Home2 Suites by Hilton San Francisco Airport North. There are 22 options on our site to choose from.
Which South San Francisco hotels do our guests like for their central location?
Travelers like DoubleTree by Hilton San Francisco South Airport Blvd for its great location.
Where should I stay in South San Francisco if I'm looking for a reasonably priced accommodation?
La Quinta Inn & Suites by Wyndham San Francisco Airport N is an accommodation you might want to consider that’ll save you money. You can browse all 18 choices on our site.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, review our selection of 63 vacation homes. In addition, you can choose from 10 apartments.
Where can I stay if I'm traveling to South San Francisco with my children?
Parents traveling with children may want to consider La Quinta Inn & Suites by Wyndham San Francisco Airport N, Embassy Suites San Francisco Airport - South San Francisco and Best Western Plus Grosvenor Airport Hotel. You can also see 8 options available on our site.
Where should I stay in South San Francisco for a getaway with my partner?
Inn At Oyster Point, La Quinta Inn & Suites by Wyndham San Francisco Airport N and Comfort Inn and Suites San Francisco Airport North are great options for a romantic getaway. You can also check out all 8 options on our site.
Where should I stay in South San Francisco if I want a luxurious hotel?
An option for a luxury stay is DoubleTree by Hilton San Francisco South Airport Blvd. Additionally, check out all 9 options on our site.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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